2,4-Dichloropyrido[3,2-d]pyrimidine - Names and Identifiers
Name | 2,4-Dichloropyrido[3,2-d]pyrimidine
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Synonyms | 4-dichloropyrido[3 5,6-DIMETHYLPYRAZI... 2,4-dichloropyrido[3,2-d]pyrimidine 2,4-Dichloropyrido[3,2-d]pyrimidine Pyrido[3,2-d]pyrimidine, 2,4-dichloro-
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CAS | 39551-54-7
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InChI | InChI=1/C7H3Cl2N3/c8-6-5-4(2-1-3-10-5)11-7(9)12-6/h1-3H |
2,4-Dichloropyrido[3,2-d]pyrimidine - Physico-chemical Properties
Molecular Formula | C7H3Cl2N3
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Molar Mass | 200.02 |
Density | 1.573 |
Melting Point | 168-169 ºC |
Boling Point | 286.111°C at 760 mmHg |
Flash Point | 154.152°C |
Vapor Presure | 0.005mmHg at 25°C |
pKa | -1.31±0.30(Predicted) |
Storage Condition | Inert atmosphere,Store in freezer, under -20°C |
Refractive Index | 1.682 |
MDL | MFCD11046863 |
2,4-Dichloropyrido[3,2-d]pyrimidine - Risk and Safety
Hazard Symbols | T - Toxic
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Risk Codes | 25 - Toxic if swallowed
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Safety Description | 45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
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2,4-Dichloropyrido[3,2-d]pyrimidine - Introduction
2,4-Dichloropyrido[3,2-d]pyrimidine is an organic compound with the chemical formula C8H4Cl2N2. It is a white solid, odorless, insoluble in water. The following is a detailed description of its nature, use, preparation and safety information:
Nature:
-Appearance: White solid
-Molecular weight: 199.04g/mol
-Melting point: 136-141°C
-Boiling point: 392.2°C
-Density: 1.46g/cm³
-Insoluble in water, slightly soluble in organic solvents such as ethers and alcohols
Use:
- 2,4-Dichloropyrido[3,2-d]pyrimidine is often used as an intermediate in organic synthesis to participate in the synthesis of other compounds.
-It is often used to synthesize organic compounds such as drugs, pesticides and dyes.
Preparation Method:
The preparation method of 2,4-Dichloropyrido[3,2-d]pyrimidine is more complicated. The following is a possible preparation method:
1. First, a chlorine atom is introduced into the pyridine ring by reaction to prepare 2,4-dichloropyridine.
2. then 2,4-dichloropyridine and 2,4,5-trichloropyridine are cyclized to generate 2,4-Dichloropyrido[3,2-d]pyrimidine.
Safety Information:
- 2,4-Dichloropyrido[3,2-d]pyrimidine is toxic and may pose a health hazard.
-Appropriate safety measures should be taken during operation, including wearing appropriate personal protective equipment (such as protective glasses, gloves and lab clothes).
-Avoid contact with skin, eyes and respiratory tract, and avoid inhalation or ingestion.
-It should be operated in a well-ventilated place to avoid dust or vapor.
-Waste should be disposed of in accordance with local regulations.
Please note that when using and handling 2,4-Dichloropyrido[3,2-d]pyrimidine, you should follow the correct experimental practices and follow relevant safety guidelines and regulations.
Last Update:2024-04-09 15:17:58